Kontakt
Jak kupować
Dostawa
Doradca ds. zakupów
Computational Methods for Fragment Spectrum Interpretation
Computational Interpretation of Tandem MS Spectra Including Fragment Ions with Post-Translational Modifications
Angielski
124 b
najlepszej
ceny ▸
Nawet do 30 dni na zwrot
Klienci kupili także
/
Miękka
64.03
zł
Post-translational modifications (PTMs) are of critical importance for a vast range of cellular processes such as growth control and signal transduction. Mass spectrometry (MS) can shed light on the characteristics of PTMs to gain insight into the mechanisms of numerous diseases including cancer. However, interpretation of tandem MS spectra including fragment ions with PTMs from high-throughput experiments is a complex challenge. The high number and diversity of known PTMs as well as suboptimal quality of spectra compromise the identification of PTMs in MS experiments. In this book, an efficient algorithm for the computational interpretation of tandem MS spectra including fragment ions with PTMs is described. Information on both precursor and fragment ion level is utilized and an arbitrary number of PTMs is considered. A robust statistical noise intensity model is developed to compensate for low spectrum quality. Finally, the algorithm is successfully applied on the fragment spectra in the PRIDE proteomics data repository to render it suitable for statistical machine learning investigations.
Informacje o książce
Angielski
Podaruj tę książkę jeszcze dziś
To łatwe
1 Dodaj książkę do koszyka i wybierz „dostarczyć jako prezent” 2 W odpowiedzi wyślemy Ci bon 3 Książka dotrze na adres obdarowanegoMogłoby Cię także zainteresować
/
Miękka
87.79
zł
/
Miękka
91.16
zł
/
Miękka
40.58
zł
/
Miękka
191.70
zł
/
Miękka
32.93
zł
/
Miękka
302.96
zł
/
Miękka
287.26
zł
/
Miękka
44.45
zł
/
Miękka
49.96
zł
Cześć! Jestem Libroamiko, Twój doradca książkowy.
Jak mogę Ci pomóc?