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Provided here is an easily accessible introduction to the§mechanisms of DNA replication, regulation and the§biochemistry of cell cycle control. An overview of this§rapidly developing field is presented to orient the reader,§followed by a series of contributions by leading researchers§summarizing recent results on selected topics, such as§protein phosporylation, tumor suppressor genes, and signal§transduction in prokaryotic and eucaryotic systems. The§reader will gain an overview of our current understanding of§DNA replication and the cell cycle, and a selection of§useful recent references for further reading.