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The removal of organic debris is the main purpose of pulpectomy in primary teeth. The goal can be achieved with manual or pediatric rotary file instrumentation. Considering that the preparation time of the root canal is an important clinical factor in pediatric patient management, so the use of pediatric rotary instruments for pulpectomy in primary teeth is recommended. The clinician must choose the strategies, instruments, and devices to deal with these challenges and to control the preparation of the shape, length, and width precisely. The development of new files is a fast and market-driven process. Practitioners or pediatric dentists must always bear in mind that all file systems have benefits and weaknesses. The pediatric rotary files system will help the dentist in performing the pulpectomy procedure faster and easier. These instrumentation techniques are considered effective to debride the uneven walls of root canals of primary teeth. The root canal preparation with this file system has consistently resulted in uniform and predictable quality of obturation in lesser time.