​Theoretical and Clinical Geropharmacology​

This book explores the emerging field of senotherapeutics, which focuses on targeting cellular senescence to reduce age-related diseases and promote healthy aging. As the population ages, there is growing interest in developing senotherapeutic strategies to delay or reverse age-related degenerative processes. Senotherapeutics offers promising approaches to achieve this goal by addressing the key factors that drive cellular aging. Fundamental mechanisms of cellular senescence, the potential of senolytic and senomorphic compounds in integrating senescence-associated pathways, and their relevance in conventional geropharmacology are offered to the readers. The current volume also highlights recent advances, challenges, and future directions, emphasizing developing senotherapeutic medications to promote longevity and improve healthspan.

• To better understand the nature of senotherapeutic agents and related cellular signaling cascades in health life-span maintenance and age-associated pathologies.
• To pioneer new candidate senotherapeutic drugs that can be developed based on current scientific knowledge.
• To reveal the repurposed conventional drugs in the elderly patient group, and to propose new drug-based therapeutic strategies suitable for the advanced age group