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Opis

In this work surface modifications were developed that bear cell-adhesive as well as antimicrobial properties. Fast cell adhesion and wound healing is desired for biomaterials since otherwise the material would be recognized as a foreign body and infectious bacteria could enter the cavity between material and tissue. Plasma polymerization was used as the deposition technique since a broad range of materials can be coated independent of their composition. As a cell-adhesive coating plasma polymerized allylamine was chosen since it is cell-friendly and offers a platform for wet chemical modifications such as grafting of fibronectin. Furthermore, it serves as a barrier layer for zinc and silver containing sub-layers that exhibit antimicrobial properties due to the release of zinc and silver. The layer systems were spectroscopically and microscopically investigated. Cell-adhesive and antimicrobial properties were tested with various types of cells and bacteria.

Szczegóły książki

Kategoria Książki po angielsku Mathematics & science Biology, life sciences Biochemistry

• Pełny tytuł: Designing an antimicrobial and cell-adhesive multilayer
• Autor: Alexander Lotz
• Język: Angielski
• Oprawa: Miękka
• Liczba stron: 132
• EAN: 9783838133430
• ISBN: 3838133439
• ID: 06997139
• Wydawca: Sudwestdeutscher Verlag Fur Hochschulschriften AG
• Waga: 204 g
• Wymiary: 229 × 152 × 8 mm
• Data wydania: 25. May 2012

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