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Opis

A magisterial survey of all aspects of the reverse transcriptase inhibitors (RTIs) used to treat HIV/AIDS, including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. The authors synthesize our current understanding of the role of reverse transcriptase in the viral life cycle, describe the discovery and development of eight nucleoside and nucleotide analogs that represent milestones in treatment history, and thoroughly discuss the question of toxicity and resistance to this class of drugs. They also address three non-nucleoside RTIs and their pharmacokinetics and comparative clinical efficacy, new RTIs currently under development, and the impact of approved agents on treatment, in general, and on vertical transmission in the developing world.

Szczegóły książki

Kategoria Książki po angielsku Medicine Clinical & internal medicine Diseases & disorders

• Pełny tytuł: Reverse Transcriptase Inhibitors in HIV/AIDS Therapy
• Autor: kowron
• Język: Angielski
• Oprawa: Twarda
• Liczba stron: 528
• EAN: 9781588296498
• ISBN: 1588296490
• ID: 01430558
• Wydawca: Humana Press Inc.
• Waga: 967 g
• Wymiary: 235 × 155 × 34 mm
• Data wydania: 01. May 2006

Ulubione w innej kategorii

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