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Book synopsis

Communication between cells as a prerequisite for life of multicellular organisms is achieved mostly by solvent mediators like hormons, neurotransmitters, cytokines and chemokines. Increasing evidence suggests that a class of cytokines exists that signals from immune cells specifically towards epithelial cells. The most prominent member of these "tissue-signaling cytokines" is Interleukin-17 (IL-17). This book illustrates IL-17 is essential to protect the human organism at its skin surface against invading microorganisms. Cellular sources of IL-17 and trigger factors of IL-17 secretion in the skin are defined. Finally, this book identifies two human diseases associated with chronic infections of the skin that are at least partially caused by a disturbed IL-17 pathway the orphan syndrome "chronic mucocutaneous candidiasis" and the very common inflammatory skin disease "atopic dermatitis/ eczema".

Book details

Book category Books in English Medicine Medicine: general issues

• Full title: Interleukin-17 Is a Key Cytokine in First-Line Defence of the Skin
• Author: Kilian Eyerich
• Language: English
• Binding: Paperback
• Number of pages: 92
• EAN: 9783838117560
• ISBN: 3838117565
• ID: 02271661
• Publisher: Sudwestdeutscher Verlag Fur Hochschulschriften AG
• Weight: 145 g
• Dimensions: 229 × 152 × 7 mm
• Date of publishing: 12. July 2010

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