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Opis

Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector.§§The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).§§The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.§§Concisely summarizes the therapeutic implications of recent, large-scale epigenome studies, including the cancer epigenome atlas§Discusses targeted isoform specific versus pan-specific inhibitors, a rational drug design approach to epigenetics relevant to pharmacoepigenetic clinical applications§Covers new findings in the interplay between cancer stem cells (CSCs) and drug resistance, demonstrating that epigenetic machinery is a candidate target for the eradication of these CSCs

Szczegóły książki

Kategoria Książki po angielsku Medicine Pre-clinical medicine: basic sciences Anatomy

• Pełny tytuł: Epigenetic Cancer Therapy
• Autor: Steven Gray
• Język: Angielski
• Oprawa: Twarda
• Liczba stron: 748
• EAN: 9780128002063
• ISBN: 0128002069
• ID: 09240325
• Wydawca: Elsevier Books
• Waga: 1722 g
• Wymiary: 200 × 242 × 42 mm
• Data wydania: 24. August 2015

Ulubione w innej kategorii

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